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In certain embodiments, provided herein is an antibody that immunospecifically binds CRBN and comprises a heavy chain having the amino acid sequence depicted in SEQ ID NO 5, or the VH domain, VH CDR1, VH CDR2, and or VH CDR3 thereof <a href=https://enhanceyourlife.mom/>priligy</a> 2005 Feb; 65 2 261 71